Venomic and pharmacological activity of Acanthoscurria paulensis (Theraphosidae) spider venom
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چکیده
منابع مشابه
Pharmacological Characterization of the Edema Caused by Vitalius dubius (Theraphosidae, Mygalomorphae) Spider Venom in Rats.
Bites by tarantulas (Theraphosidae, Mygalomorphae) in humans can result in mild clinical manifestations such as local pain, erythema, and edema. Vitalius dubius is a medium-sized, nonaggressive theraphosid found in southeastern Brazil. In this work, we investigated the mediators involved in the plasma extravasation caused by V. dubius venom in rats. The venom caused dose-dependent (0.1-100 μg/s...
متن کاملOntogenesis, gender, and molting influence the venom yield in the spider Coremiocnemis tropix (Araneae, Theraphosidae)
The demand for spider venom increases along with the growing popularity of venoms-based research. A deeper understanding of factors that influence the venom yield in spiders would therefore be of interest to both commercial venom suppliers and research facilities. The present study addresses the influence of several factors on the venom yield by systematically analyzing the data obtained from 1...
متن کاملThe spider genera Euthycaelus Simon and Schismatothele Karsch (Mygalomorphae, Theraphosidae).
The genus Euthycaelus Simon 1889 is diagnosed based on the examination of type-material and additional material from Venezuela and Colombia. The genus now includes: Euthycaelus colonicus Simon 1889, E. norae sp. nov., E. amandae sp. nov.; Euthycaelus steini Simon 1889 is transferred to Psalistops comb. nov. The genus Schismatothele Karsch 1879 is considered a senior synonym of Hemiercus Simon 1...
متن کاملAntimicrobial activity of the toxin VdTX-I from the spider Vitalius dubius (Araneae, Theraphosidae)
Background Currently there is an urgent need to develop new classes of antimicrobial agents with different mechanisms of action from conventionally antibiotics used for the control of pathogenic microorganisms. The acylpolyamine called VdTX-I was isolated from the venom of the tarantula Vitalius dubius, and first described with activity as an antagonist of nicotinic cholinergic receptors. The m...
متن کاملSpider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads.
Voltage-gated sodium (Na(V)) channels play a central role in the propagation of action potentials in excitable cells in both humans and insects. Many venomous animals have therefore evolved toxins that modulate the activity of Na(V) channels in order to subdue their prey and deter predators. Spider venoms in particular are rich in Na(V) channel modulators, with one-third of all known ion channe...
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ژورنال
عنوان ژورنال: Toxicon
سال: 2013
ISSN: 0041-0101
DOI: 10.1016/j.toxicon.2012.11.008